However, loss of overall diversity due to domestication process can decrease a population’s peptide repertoire. A higher MHC allele diversity in a population will allow presenting a broader peptide repertoire. 6Infectious and Tropical Diseases Research Group (e-INTRO), Biomedical Research Institute of Salamanca-Research Centre for Tropical Diseases at the University of Salamanca (IBSAL-CIETUS), Faculty of Pharmacy, University of Salamanca, Salamanca, Spainīovine leukocyte antigens (BoLA) have been used as disease markers and immunological traits in cattle due to their primary role in pathogen recognition by the immune system.5Basic Sciences Department, School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, Colombia.
4Faculty of Agricultural Sciences, Universidad de Ciencias Aplicadas y Ambientales (UDCA), Bogotá, Colombia.3PhD Programme in Biomedical and Biological Sciences, Universidad del Rosario, Bogotá, Colombia.2Molecular Biology and Immunology Department, Fundación Instituto de Inmunología de Colombia (FIDIC), Bogotá, Colombia.1Microbiology Postgraduate Programme, Universidad Nacional de Colombia, Bogotá, Colombia.2101-2104ĭomestication, Bos taurus, coalescent simulation, ancient DNA, approximate Bayesian computation National Categoryīiological Sciences Identifiers URN: urn:nbn:se:uu:diva-182770 DOI: 10.1093/molbev/mss092 ISI: 000308851600003 OAI: oai:DiVA.Michel David Bohórquez 1,2†, Diego Ordoñez 3,4†, Carlos Fernando Suárez 2,5, Belén Vicente 6, Carmen Vieira 6, Julio López-Abán 6, Antonio Muro 6, Iván Ordóñez 2 and Manuel Alfonso Patarroyo 2,5* Place, publisher, year, edition, pages2012.
Such a low number is consistent with archaeological data indicating that initial domestication took place in a restricted area and suggests the process was constrained by the difficulty of sustained managing and breeding of the wild progenitors of domestic cattle.
#TAURINE CATTLE SERIAL#
We report mtDNA sequences from 15 Neolithic to Iron Age Iranian domestic cattle and, in conjunction with modern data, use serial coalescent simulation and approximate Bayesian computation to estimate that around 80 female aurochs were initially domesticated. A large number would be expected if cattle domestication was a technologically straightforward and unexacting region-wide phenomenon, while a smaller number would be consistent with a more complex and challenging process. However, while modern mitochondrial DNA (mtDNA) variation indicates early Holocene founding event(s), a lack of ancient DNA data from the region of origin, variation in mutation rate estimates, and limited application of appropriate inference methodologies have resulted in uncertainty on the number of animals first domesticated. 2101-2104 Article in journal (Refereed) Published Abstract Īrchaeozoological and genetic data indicate that taurine cattle were first domesticated from local wild ox (aurochs) in the Near East some 10,500 years ago. Show others and affiliations 2012 (English) In: Molecular biology and evolution, ISSN 0737-4038, E-ISSN 1537-1719, Vol.
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